Dr. Daniella Rylander is a young preclinical research scientist from Lund University, Sweden, with particular interest in Parkinson’s disease and dyskinesia. Her current research focuses on the integration of transplanted precursor neurons into the striatum and the possible contribution to graft-induced dyskinesia.The project involves collaborators in both Sweden and Italy. Daniella did her PhD, (2006-2010), in the group of Professor Angela Cenci-Nilsson, working on L-DOPA-induced dyskinesia in the rat model. She specifically evaluated two non-dopaminergic systems: serotonin and glutamate, in the occurrence of L-DOPA-induced dyskinesia. One of the main findings demonstrated a relatively high density of serotonin fibres in the striatum of dyskinetic subjects that linked a maladaptive plasticity of the serotonin system to dyskinetic complications. With this study, Daniella was honoured the ”Melvin Yahr International Young Scientist Award” at WFN World Congress on Parkinson’s disease and related disorders in Amsterdam, 2007. At the congress in Miami two years later, she was invited to give a platform presentation on how a metabotropic glutamate receptor (mGluR5) antagonist reduces L-DOPA-induced dyskinesia in both rat and primate model of Parkinson’s disease. Daniella’s PhD thesis was highlighted in several medical newspapers and was awarded the Swedish “Elsa & Inge Andersson Price” for best PhD thesis, which partly finances her ongoing research.
Presentations by Daniella Rylander currently available on MultiWebcast.com
Plenary Sessions - XIX World Congress on Parkinson's Disease and Related Disorders
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