The Pro12Ala Polymorphism of Peroxisome Proliferator Activated Receptor Gene y-2 (PPAR Gamma-2) is Associated with Increased Insulin Sensitivity in HIV-infected Patients on Antiretroviral Therapy
Dr. Vicente Estrada
15 slide(s) – 00:08:27 – English – 2007-10-25
Genetic factors may modulate insulin resistance in HIV patients on ART
Insulin resistance in HIV infected patients on antiretroviral therapy (ART) is associated to the presence of Pro12Ala polymorphism, a common genetic variation observed in 13% of caucasian population; insulin resistance is also related to an increased weight, a prolonged ART, and also HIV/HCV coinfection.