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The Pro12Ala Polymorphism of Peroxisome Proliferator Activated Receptor Gene y-2 (PPAR Gamma-2) is Associated with Increased Insulin Sensitivity in HIV-infected Patients on Antiretroviral Therapy Dr. Vicente Estrada, Spain
- Biography
English - 2007-10-25
Insulin resistance in HIV infected patients on antiretroviral therapy (ART) is associated to the presence of Pro12Ala polymorphism, a common genetic variation observed in 13% of caucasian population; insulin resistance is also related to an increased weight, a prolonged ART, and also HIV/HCV coinfection.
Learning objectives
Genetic factors may modulate insulin resistance in HIV patients on ART
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