Renal Function and Size at the Age of 7 Years of Extremely Low Birth Weight Infants
2010-10-25 - English

P. Kwinta(1), M. Klimek(1), A. Grudzień(1), M. Jagła(1), D. Drożdż(2), J.J. Pietrzyk(1)
(1)Department of Pediatrics, (2)Department of Nephrology, Jagiellonian University Medical College, Cracow, Poland

Background:
Prematurity is considered to be...(more)

Continuous Renal Replacement Therapy After Cardiac Surgery in Children
2010-10-25 - English

M.J. Santiago, J. López-Herce, J. del Castillo, A. Sánchez, J. Urbano, M. Botrán, A. Carrillo
Pediatric Intensive Care Unit, Hospital General Universitario Gregorio Marañón, Madrid, Spain

Objective:
To study the evolution of children requiring continuous renal...(more)

Glomerular Hyperfiltration Injury in Children with a Solitary Functioning Kidney: A Prediction Model . The Kimono-Study
2010-10-25 - English

R. Westland(1), M.F. Schreuder(2), M.D. Spreeuwenberg(3), A. Bökenkamp(1), J.A.E. van Wijk(1)
(1)Pediatric Nephrology, VU University Medical Center, Amsterdam, (2)Pediatric Nephrology, UMCN St Radboud, Nijmegen, (3)Clinical Epidemiology and Biostatistics, VU University...(more)

Prevention of Renal Scarring
2010-10-25 - English

PRO and CON
2010-10-25 - English

A PROSPECTIVE STUDY OF IN-HOSPITAL PEDIATRIC CARDIAC ARREST IN EUROPEAN AND LATINOAMERICAN HOSPITALS
2010-10-25 - English

J. del Castillo Peral(1), J. López-Herce Cid(2), European and Latinoamerican Study Group of Cardiac Arrest in Children
(1)Servicio de Cuidados Intensivos Pediátricos, Hospital General Universitario Gregorio Marañón., (2)Red Iberoamericana de Estudio de la Parada...(more)

NATURE, FREQUENCY AND DETERMINANTS OF CLINICAL PHARMACY INTERVENTIONS IN ELECTRONIC MEDICATION PRESCRIPTIONS FOR PEDIATRIC INPATIENTS
2010-10-25 - English

B. Maat(1), Y.S. Au(2), C.W. Bollen(3), A.J. van Vught(3), A.C.G. Egberts(1,2), C. Rademaker(1)
(1)Department of Clinical Pharmacy, UMC Utrecht, (2)Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences, Utrecht University,...(more)

ASSESSMENT OF THE PEDIATRIC INDEX OF MORTALITY 2 (PIM2) SCORE WITH THE PAO2/FIO2 RATIO DERIVED FROM THE SPO2/FIO2 RATIO
2010-10-25 - English

Normal and abnormal brain development
2010-10-25 - English

CLINICAL GOVERNANCE: USE OF GUIDELINES IN PRE-HOSPITAL CARE
2010-10-25 - English

Introduction
2010-10-25 - English

PATIENT SAFETY AND QA
2010-10-25 - English

Biochemical and Non-Invasive Brain Monitoring in Newborns whose Mothers Used Antidepressants Drugs During Pregnancy
2010-10-24 - English

V. Bellissima(1), S. Miriam1, M. Colivicchi1, F. Guerriero(1), M. Strozzi1, T. Ververs(2), F. van Bel(3), D. Gazzolo(1)
(1)Ospedale Infantile Cesare Arrigo, Alessandria, Italy, (2)University Medical Center Utrecht, (3)University Medical Center Utrecht, Wilhelmina...(more)

Clinical and Growth Outcomes From the DINO (DHA for the Improvement of Neurodevelopmental Outcome in Preterm Infants) Trial
2010-10-24 - English

C.T. Collins(1,2), B.J. Manly(3,4), R.A. Gibson5, T.R. Sullivan(6), P. Ryan(6), A.J. McPhee(7), P.G. Davis(3,4), M. Makrides(1,2), the DINO Steering Committee
(1)Child Nutrition Research Centre, Women\'s and Children\'s Health Research Institute, North Adelaide,...(more)

Should Infants Who Have Early Major Surgery Be Enrolled in Follow-Up Clinics?
2010-10-24 - English

K. Walker(1,2), R. Halliday(1), A.J. Holland(2,3), D. Winlaw(2,4), G. Sholler(2,4), N. Badawi(1,2,5,6)
(1)Grace Centre for Newborn Care, The Children\'s Hospital at Westmead, (2)The University of Sydney, (3)Department of Surgery, (4)Adolph Basser Cardiac Institute, The...(more)

Long Term Effects: Follow-Up Programmes
2010-10-24 - English

Subtle Outcomes Following Perinatal Asphyxia
2010-10-23 - English

Neonatal encephalopathy may be associated with problems other than cerebral palsy, such as cognitive and behavioral problems and problems regarding executive function and memory. To be able to regocnize these problems,follow-up needs to be continues well into childhood.

Subtle Outcomes Following Preterm Birth
2010-10-23 - English

Predicting Feeding Problems in Infants with Central Grey Matter Damage Following Hypoxic-Ischaemic Encephalopathy (HIE)
2010-10-23 - English

M. Martinez-Biarge(1,2), J. Diez-Sebastian(3), S. Lawrence(4), A. Aloysius(4), M.A. Rutherford5, F.M. Cowan(1)
(1)Paediatrics and Imaging Sciences, Imperial College London, London, UK, (2)Neonatology, (3)Statistics, La Paz University Hospital, Madrid, Spain, (4)Speech and...(more)

Acute Inflammatory Injury of Immature Cerebral White Matter Assessed by Spectroscopy at 9.4T
2010-10-23 - English

G. Lodygensky(1), N. Kunz(2), S. Sizonenko(3), R. Gruetter(2), P.S. Hüppi(3)
(1)Pediatrics, NICU, University of Geneva, Geneva, (2)LIFMET, CIBM, Ecole Polytechnique de Lausanne, Lausanne, (3)Pediatris, Division of Development and Growth, University of Geneva, Geneva,...(more)

Morbidity and Mortality Following Infant Vaccinations in Low-Income Countries
2010-10-23 - English

Opening Words
2010-10-23 - English

Opening Words
2010-10-23 - English

Opening Words
2010-10-23 - English

Opening Words
2010-10-23 - English

Opening Words
2010-10-23 - English

Incidence, Risk Factors and Severity of Pulmonary Morbidity in Infants with Congenital Diaphragmatic Hernia Born in High-Volume Centers in Europe
2010-10-23 - English

L. van den Hout(1), I. Reiss1, T. Schaible(2), I. Capolopu(3), A. van Heijst(4), M. Gorett Silva(5), K. Allegaert(6), A. Greenough(7), D. Tibboel(1)
(1)Intensive Care and Paediatric Surgery, ErasmusMC-Sophia, Rotterdam, The Netherlands, (2)Paediatric Intensive Care,...(more)

MATERNAL DEPRESSION: IMPLICATION FOR ASTHMA MANAGEMENT IN CHILDREN
2010-10-23 - English
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Aim: To identify the relationship between maternal depression, the health and well being of children with asthma, and the role of the pediatric nurse.
Method: Review of the medical and nursing literature.
Results: Adult...(more)

IMPACT OF CHILDHOOD CHRONIC ILLNESSES ON SIBLINGS: A SYSTEMATIC LITERATURE REVIEW
2010-10-23 - English
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Background: Childhood chronic illness can have a significant impact on siblings of ill children. The aim of this review was to identify, appraise and synthesise the literature in order to examine the impact of childhood chronic illness or disability on...(more)

ON YOUR OWN FEET AHEAD: INNOVATIONS IN DUTCH TRANSITIONAL CARE FOR ADOLESCENTS WITH CHRONIC CONDITIONS
2010-10-23 - English
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Background: In the Netherlands, adolescents with chronic conditions are often ill prepared for their transition to adult care. Research revealed that services are not geared toward adolescents\' needs and preferences. To bridge these gaps, a four-year innovation...(more)

TRANSITION FROM CHILD TO ADULT CARE FOR YOUNG PEOPLE WITH MENTAL HEALTH PROBLEMS: A PROCESS OF TRANSITION
2010-10-23 - English
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The transition of young people from child to adult healthcare services has become increasingly important. Evidence suggests that the process is often poorly managed and many young people with mental health problems experience abrupt ad hoc transitions from child to adult...(more)

COVARIATES OF NURSES\' MANAGEMENT OF PAIN IN CHILDREN
2010-10-23 - English
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Introduction: Effective implementation of an evidence based pain policy for children is affected by nurses\' knowledge of, attitudes towards and self-efficacy. Since nurses from different departments and with different levels of education manage pain in children, we...(more)

DID PAEDIATRIC EARLY WARNING SYSTEM(PEWS) UTILISATION IMPACT ON SEVERITY OF ILLNESS AND OUTCOME FOR PATIENTS ADMITTED TO A TERTIARY PICU?
2010-10-23 - English
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Introduction: PEWs was implemented at Alder Hey in August 2006. No screening tool was being used at District General Hospitals at that time. There has been no comparative data to date exploring the impact of such innovations on the severity of illness at first...(more)

FAMILIAL AGGREGATION AND HERITABILITY OF PYLORIC STENOSIS
2010-10-23 - English
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Background: Pyloric stenosis is the most common condition requiring surgery in the first months of life. Familial aggregation has been reported. However, to what extent this is caused by common environment or inheritance is unknown.
Aims: To investigate familial...(more)

OROFACIAL CLEFTS AND ASSOCIATED CARDIAC ANOMALIES: THE 18 YEARS EXPERIENCE OF A MULTIDISCIPLINARY GROUP IN A TERTIARY HOSPITAL IN PORTUGAL
2010-10-23 - English
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Introduction: Orofacial clefts are a heterogeneous group of disorders arising in about 1.7/1000 newborns. They can occur with other congenital anomalies, including heart disease.
Aim: To describe a population with orofacial clefts and...(more)

POLYMORPHISMS IN\' UGT1A1 \'GENE AMONG NORTH INDIAN NEONATES PRESENTING WITH UNCONJUGATED HYPERBILIRUBINEMIA
2010-10-23 - English
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Objective: Genetic factors are implicated in pathogenesis of neonatal hyperbilirubinemia. The present study was conducted to determine the frequency of (TA)n promoter polymorphism and Gly71Arg mutation in UGT1A1 gene in North Indian neonates ?35-week...(more)

SEX AND GENDER IN SPORT: FALLACY OF THE
2010-10-23 - English
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There is controversy regarding participation in high profile competitive events by female athletes perceived as inappropriately \"masculine\" by competitors and others. Over 50 years, international sports bodies such as the International Olympic Committee (IOC) and the...(more)

Q-CARE PROFILES: DEVELOPMENT OF A NEW INSTRUMENT TO STIMULATE COMMUNICATION WITH ADOLESCENTS WITH CHRONIC DISORDERS DURING CONSULTATIONS
2010-10-23 - English
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Background: A previous Q-methodological study revealed four distinct preference profiles for health care delivery and self-management: \'Conscious & Compliant\'; \'Backseat Patient\'; \'Self-confident & Autonomous\'; and \'Worried & Insecure\'.
Aim: ...(more)

CHALLENGES IN CHILD SEXUAL ABUSE HUNGARY
2010-10-23 - English
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Objective: Between 1986 and 2005, 266 girls under the age of 18 had been exposed to sexual abuse. We summarize the characteristics of child sexual abuse cases and explore common features.
Methods: We prospectively collected data according to...(more)

FETAL GROWTH, PRETERM BIRTH, NEONATAL STRESS AND RISK FOR CNS TUMORS IN CHILDREN: A NORDIC POPULATIONAND REGISTER-BASED CASE-CONTROL STUDY
2010-10-23 - English
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We investigated the association between indicators of fetal growth and neonatal stress and CNS tumours diagnosed in the Denmark, Sweden, Norway and Finland in 1985-2006, using data from national cancer registries and medical birth registries. We included 3,443 children with...(more)

NEUROSENSORY IMPAIRMENT AND TREAMENT OF PATENT DUCTUS ARTERIOSUS IN EXTREMELY LOW BIRTH WEIGHT INFANTS
2010-10-23 - English
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Background and aim: There is controversy in the last years on on surgical closure of the ductus arteriosus in extremely low birth weight infants. Study the possible consequences of surgical closure of the patent ductus arteriosus in the newborn...(more)

CSF-LACTATE AS A MARKER OF MITOCHONDRIAL DISORDERS EVEN IN CHILDREN AFTER BRIEF SEIZURES
2010-10-23 - English
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Background: An increased level of lactate in body fluids serves as a biochemical marker in assessing patients with inherited metabolic disease; especially in children with mitochondrial disorders that arise from isolated or combined defects of respiratory chain...(more)

DEVELOPMENT OF CHILDREN WITH INTRACRANIAL HEMORRHAGE BORN AFTER VACUUM EXTRACTION
2010-10-23 - English
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Aim: to describe the long term follow-up of children with an intracranial hemorrhage (ICH) associated with vacuum extraction.
Methods: retrospective database search (1999-2007). Patient outcome was evaluated using the Bayley Scale of Infant Development (BSID-II-NL), or if...(more)

PREDICTORS OF DECREASED FLUID TOLERANCE IN VLBW INFANTS
2010-10-23 - English
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Objective: The goal was to elucidate predictors of decreased fluid tolerance (DFT) in very low birth weight (VLBW) infants. We hypothesized that the fluid retention is linked to severity of pulmonary problems and prolonged respiratory support, especially to...(more)

HYPERBILIRUBINEMIA IN A NATIONAL COHORT OF EXTREMELY PREMATURE INFANTS
2010-10-23 - English
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Background and aims: Hyperbilirubinemia is a possible risk factor for adverse neurodevelopmental outcome in extremely premature infants. The study was undertaken to analyse the frequency, severity and treatment of hyperbilirubinemia in such infants....(more)

WHEN TO TREAT NEONATAL JAUNDICE: IS THERE ANY EVIDENCE?
2010-10-23 - English
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Objectives: To analyse if the currently used jaundice action charts are evidence based.
Methods: We contacted 72 neonatal units in the Great Britain and enquired about the unit guidelines for management of neonatal jaundice. The jaundice...(more)

PHOTOTHERAPY (PT) IN THE NEAR-TERM NEWBORN (NB): ARE THE GUIDELINES SUFFICIENT? CURRENT PRACTICE IN SWITZERLAND
2010-10-23 - English
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Background: PT for hyperbilirubinemia in the NB is well established. Guidelines (GL) are based on the updated latest AAP guidelines. This is a 1^st step to evaluate current ICU practice
Method: A survey of cardiopulmonary side-effects (CPSE)...(more)

EXCESSIVELY HIGH BILIRUBIN AND EXCHANGE TRANSFUSION IN VERY LOW BIRTH WEIGHT INFANTS
2010-10-23 - English
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Objective: To evaluate the distribution of peak serum bilirubin levels in very low birth weight (VLBW) infants and the performance of exchange transfusion in infants with excessively high bilirubin levels.
Methods: A population based...(more)

EFFECTS OF BLOOD SAMPLING ON CEREBRAL TISSUE OXYGENATION INDEX (TOI) IN VLBW INFANTS: VENEPUNCTURE VERSUS HEEL LANCE
2010-10-23 - English
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Background and aims: In term neonates venepuncture is considered less painful than heel lance for blood sampling. Here, we compared the effects of venepuncture and heel lance blood sampling in preterm infants < 1500 g birth weight.
Methods: Twenty infants (median [range]...(more)

CEREBRO-SPLANCHNIC OXYGENATION IN EXTREMELY PRETERM INFANTS AND ITS CORRELATION WITH ENTERAL FEEDING
2010-10-23 - English
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Background: Early feeding of extremely preterm (EP) infants is essential for the development of the gastrointestinal tract. Nevertheless, optimal feeding strategy is unclear. Near infrared spectroscopy (NIRS), measuring cerebro-splanchnic oxygenation ratio...(more)

EXPRESSION OF NO SYNTHASES AND REDOX ENZYMES IN UMBILICAL ARTERIES FROM NEWBORNS BORN SMALL, APPROPRIATE, AND LARGE FOR GESTATIONAL AGE
2010-10-23 - English
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Background: Modified expression of NO synthases and prooxidative and antioxidative enzymes accompany endothelial dysfunction, the first stage of atherosclerosis. Humans born small (SGA) and large (LGA) for gestational age are at higher risk to develop...(more)

RANDOMIZED CLINICAL TRIAL ON ECHOCARDIOGRAPHICALLY GUIDED (ECHOG) VERSUS STANDARD IBUPROFEN TREATMENT (SIBT) FOR PATENT DUCTUS ARTERIOSUS (PDA): PILOT STUDY
2010-10-23 - English
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Background: Pharmacological closure of PDA with SIbT protocol consists of three doses of ibuprofen (10-5-5 mg/k) given 24h apart. Associated side effects during treatment have been reported. Therefore, treatment strategies deserve further evaluation.
...(more)

CAN A GENTAMICIN SPECIFIC CHART REDUCE NEONATAL MEDICATION ERRORS?
2010-10-23 - English
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Background and aims: Since the onset of incident reporting, medication errors have been noted to be one of the most common reasons for reporting a clinical incident and antibiotics have been shown to be one of the most common drugs associated with medication...(more)

PROSPECTIVE EVALUATION OF PROPYLENE GLYCOL TOLERANCE IN (PRE)TERM NEONATES: AN ACTIVE COMPARATOR APPROACH
2010-10-23 - English
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Introduction: Propylene glycol (PG) is a commonly used excipiens although accumulation can result in hyperosmolarity, renal toxicity and lactic acidosis. This is of concern in neonates given their limited metabolic capacity [1]. We therefore evaluated renal,...(more)

SHORT TERM OUTCOMES WITH USE OF CHLORHEXIDINE GLUCONATE (CHG) AND POVIDONE-IODINE (PI) IN VLBWI WITH PERCUTANEOUSLY PLACED CENTRAL VENOUS CATHETERS
2010-10-23 - English
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YTBackground and aims: CHG´s use as a skin antiseptic in neonates is limited because of concerns about systemic absorption and potential side-effects. No chlorhexidine-based antiseptic has been approved by the FDA for neonatal IV catheter placement. We...(more)

HAEMODYNAMICS FOLLOWING INTRAVENOUS PARACETAMOL ADMINISTRATION IN (PRE)TERM NEONATES
2010-10-23 - English
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Introduction: There are recent observations on the haemodynamics of intravenous paracetamol (hypotension) in adult IC setting (1). We therefore evaluated the haemodynamics following iv paracetamol loading dose (20 mg.kg^-1) in (pre)term...(more)

COMPARING BERACTANT AND PORACTANT ALFA FOR TREATMENT OF RESPIRATORY DISTRESS IN PREMATURE NEONATES
2010-10-23 - English
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Background: Respiratory distress syndrome (RDS) is a major cause of mortality and morbidity in preterm infants. The aim of this study was to compare the complications of prematurity among preterm infants treated with two different natural surfactants.
...(more)

MODEL-BASED LIDOCAINE DOSING REGIMEN FOR SEIZURE CONTROL IN PRETERM AND TERM NEONATES
2010-10-23 - English
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Objectives: Lidocaine is administered as an anticonvulsant to neonates that are not responding to first-line anticonvulsants. For term neonates a dosing regimen has been developed (Malingre et al., 2006), but it has not been evaluated for preterm...(more)

ORAL IODINE SUPPLEMENTATION AND THYROID FUNCTION IN PREMATURE BABIES BORN LESS THAN 1500 GR OF WEIGHT
2010-10-23 - English
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Background: The trace element iodine is essential for the synthesis of thyroid hormones. Premature babies need >30 µg I / kg /day (ICCIDD recommendations). Neonates and especially preterm infants are a population at risk of suffering the consequences of...(more)

ADRENAL INSUFFICIENCY DURING PHYSIOLOGICAL STRESS IN CHILDREN AFTER KIDNEY OR LIVER TRANSPLANTATION
2010-10-23 - English
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Objective: To assess the prevalence and risk factors of adrenal insufficiency (AI) in children after kidney or liver transplantation, hospitalized for a physiological stress episode, and to identify patients that might be at risk of adrenal crises by clinical...(more)

THE T1405N CARBAMOYL PHOSPHATE SYNTHETASE POLYMORPHISM DOES NOT AFFECT PLASMA ARGININE CONCENTRATIONS IN PRETERM INFANTS
2010-10-23 - English
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Background: A C-to-A nucleotide transversion (T1405N) in the gene that encodes carbamoyl-phosphate synthetase 1 (CPS1) has been associated with changes in plasma concentrations of L-arginine in term and near term infants but not in adults. In pretem infants homozygosity for...(more)

EVALUATION OF FAT AND NITROGEN FAECAL LOSSES IN AGA AND SGA PRETERM NEWBORNS
2010-10-23 - English
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Background and aims: In preterm newborns an adequate nutrition is important to obtain a growth pattern similar to the intrauterine one, without overloading the immature metabolic and excretive functions.
The ESPGHAN guidelines for preterm enteral...(more)

NEWBORN BODY COMPOSITION ON DAY TWO OF LIFE MEASURED USING AIR-DISPLACEMENT BODY PLETHYSMOGRAPHY
2010-10-23 - English
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Background and aims: In addition to the immediate neonatal risks, fetal growth restriction has been increasingly recognised as a risk for long term metabolic disease. Most studies have relied on standardised birth weight centiles to categorise fetal growth....(more)

VALIDATION OF BIOELECTRICAL IMPEDANCE ANALYSIS WITH A THREE-COMPONENT MODEL OF BODY COMPOSITION IN 4-7 YEAR OLD CHILDREN
2010-10-23 - English
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Field methods to assess body composition in young children are scarce. The aim of this study was to validate bioelectrical impedance analysis (BIA) with the three-component (3C) model of body composition in primary school children.
We examined fifty-six 4-7 year old...(more)

IS CEREBRAL OXYGEN SUPPLY COMPROMISED IN PRETERM INFANTS UNDERGOING CLOSURE OF PATENT DUCTUS ARTERIOSUS (PDA)?
2010-10-23 - English
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Background: A hemodynamically important PDA is associated with increased morbidity and should be closed pharmacological or surgical. Studies showed that surgical closure contains a risk for adverse neurodevelopmental outcome.
Objective: To...(more)

NEUROLOGICAL DAMAGE PREDICTION BY FETAL DOPPLER PARAMETERS IN INTRAUTERINE GROWTH RESTRICTED PRETERM INFANTS
2010-10-23 - English
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Background and aims: Intrauterine growth restriction (IUGR) increases the risk for adverse neurodevelopment. While prenatal prediction of mortality is now greatly improved, prediction of neurodevelopmental morbidity remains limited. We explored the value of fetal...(more)

PREDICTING NEONATAL AND INFANT MORBIDITY AFTER PERINATAL HYPOXIC-ISCHAEMIC INJURY
2010-10-23 - English
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Background: Perinatal asphyxia is a common cause of neonatal morbidity and mortality, affecting 2-4 in 1000 term live births each year. The prediction of neurodevelopmental outcome is important for prognosis and for tailoring neuroprotective therapies to babies most...(more)

CURRENT COOLING PRACTICE IN THE UK
2010-10-23 - English
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Background and aims: The use of therapeutic hypothermia to treat neonatal encephalopathy has steadily expanded outside of clinical trial settings. The UK TOBY Cooling Register audits the use of this evolving treatment. In addition to setting standards and...(more)

DOES PHENOBARBITAL IMPROVE THE EFFECTIVENESS OF THERAPEUTIC HYPOTHERMIA IN INFANTS WITH HYPOXIC-ISCHEMIC ENCEPHALOPATHY?
2010-10-23 - English
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Objective: To determine whether Phenobarbital (PB) given before therapeutic hypothermia to infants with hypoxic-ischemic encephalopathy (HIE) augments the neuroprotective efficacy of hypothermia.
Methods: Records of 68 asphyxiated infants of...(more)

PARENTAL EDUCATION DOES NOT INFLUENCE OUTCOME OF VERY PRETERM CHILDREN ON ALL DEVELOPMENTAL DOMAINS
2010-10-23 - English
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Background: Children born preterm run an increased risk of problems on multiple domains. It is not clear how SES influences these different outcomes.
Aims: To study the relation between parental education and multiple domain outcomes at age...(more)

NEONATAL MORBIDITY IN MODERATELY PRETERM INFANTS. A SWEDISH NATIONAL POPULATION-BASED STUDY
2010-10-23 - English
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Objective: To determine the gestational age specific risks for neonatal morbidity, interventions and treatments in infants born at the crossroads between very and moderately preterm. Study design: A population-based Swedish study including 6,674 infants born at 30 to 34...(more)

HIGH FREQUENCY OF LOW SEVERITY DISABILITIES IN VERY PREMATURE INFANTS AT AGE FIVE
2010-10-23 - English
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Background: Children born preterm run an increased risk for problems on multiple domains. The co-existence of these problems needs more attention.
Aim: To investigate the prevalence of disabilities in preterm born children in comparison with term controls, and assess the...(more)

SURFACE ACTIVITY OF SMALL VOLUME AIRWAY ASPIRATES SUCTIONED DURING NEONATAL RESUSCITATION
2010-10-23 - English
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Background: Only small amounts of surfactant are be needed for measuring biophysical activity in the captive bubble surfactometer (CBS). Using large sample volumes, amniotic fluid or gastric aspirates have been used before for prediction of lung maturity in...(more)

ADVANTAGES OF \'INSURE\' METHOD IN RDS PRETERM INFANTS
2010-10-23 - English
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Background: “INSURE” (INtubation, SURfactant, Extubation) is an individualized therapy for RDS treatment of preterm infants, whose utilization in terms of efficacy and failure has not been completely defined in comparison to “rescue” mode.
Objective: ...(more)

NASAL INTERMITTENT POSITIVE PRESSURE VENTILATION VERSUS NASAL CONTINUOUS POSITIVE AIRWAY PRESSURE FOR NEONATAL RESPIRATORY FAILURE: A PROSPECTIVE, RANDOMIZED, CONTROLLED STUDY
2010-10-23 - English
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Objective To evaluate whether nasal intermittent positive pressure ventilation (NIPPV) compared with nasal continuous positive airway pressure (nCPAP) would decrease the requirement for endotracheal ventilation in the treatment of respiratory failure in preterm and...(more)

EFFECT OF TIDAL VOLUME INFORMATION AND TARGETED VENTILATOR TRAINING ON THE INCIDENCE OF HYPOCARBIA IN THE EARLY NEONATAL PERIOD
2010-10-23 - English
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Background: Hypocarbia is associated with adverse neurodevelopmental outcome in ventilated preterm infants. Most neonatal blood gas (BG) sampling is performed by pediatric trainees. We have previously shown that the monthly incidence of hypocarbia is affected by...(more)

CHARACTERISATION OF LUNG MECHANICS AFTER FETAL TRACHEAL OCCLUSION IN NEWBORN RABBITS WITH LUNG HYPOPLASIA INDUCED BY DIAPHRAGMATIC HERNIA (CDH)
2010-10-23 - English
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Aim: To assess the effects of tracheal occlusion (TO) on lung mechanics in a sham controlled newborn rabbit model of CDH.
Methods: On day 23/31, CDH was induced by ex-utero surgery. Controls received a sham thoracotomy (SHAM-CDH). On day 28...(more)

EFFECTS OF REDUCED ELECTRODE TEMPERATURE ON THE ACCURACY AND PRECISION OF TRANSCUTANEOUS CARBON DIOXIDE MEASUREMENTS
2010-10-23 - English
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Background and aims: The harmful effect of hypocapnia on the neonatal brain emphasizes the importance of monitoring arterial carbon dioxide tension (PaCO2). Transcutaneous monitoring of carbon dioxide (tcPCO2) reduces need of arterial blood sampling. Drawbacks are...(more)

ROLE OF ORAL SUCROSE IN REDUCING PAIN TO OROGASTRIC TUBE INSERTION IN PRETERM NEONATES
2010-10-23 - English
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Background and aims: The practice of orogastric tube insertion has become quite popular in NICU´s over the years. The present study was undertaken with an aim of assesing the pain associated with orogastric tube insertion across gestational age subgroups and...(more)

CLINICAL SIGNIFICANCE OF ROTAVIRUS INFECTION IN NICU: PROSPECTIVE ASSESSMENT OF 60 INFANTS
2010-10-23 - English
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Background and Aims: Although Rotavirus (RV) infection in newborns is usually asymptomatic, outbreaks have been reported, associated with increased incidence of necrotizing enterocolitis (NEC). We conducted a prospective study during the epidemic peak of RV,...(more)

NEONATAL INTENSIVE CARE UNIT COSTS OF MORBIDITIES IN VERY LOW BIRTHWEIGHT INFANTS
2010-10-23 - English
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Objective: Very low birthweight (VLBW; < 1500g weight) infants often have multiple morbidities, translating into longer neonatal intensive care unit stays and higher hospital costs. The primary aim was to examine the relationship between morbidities and the charges,...(more)

MORTALITY RISK SCORES FOR VERY-LOW-BIRTHWEIGHT INFANTS (VLBWI) ADMITTED TO A SINGLE NEONATAL UNIT (NICU) IN A 15 YEAR PERIOD
2010-10-23 - English
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Background: CRIB score was designed to assess VLBWI initial disease severity and mortality risk. Recently, its validity has been questioned and other scales used.
Aim: To assess the validity of CRIB to predict VLBWI pre-discharge mortality...(more)

CD3+CD4+-LYMPHOCYTES AS BIOMARKER PREDICTING THE OUTCOME OF PEDIATRIC HAEMATOPOIETIC STEM CELL TRANSPLANTATION RECIPIENTS
2010-10-23 - English
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Introduction: Haematopoietic stem cell transplantation (HSCT) may be complicated by severe infectious complications, graft-versus-host disease (GvHD) and relapse/graft failures depending on the lymphocyte immune reconstitution. The goal of this study was to...(more)

HIGH-DOSE FENOLDOPAM REDUCES POST OPERATIVE NGAL AND CYSTATIN C LEVELS DURING PEDIATRIC CARDIAC SURGERY
2010-10-23 - English
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Objective: Fenoldopam mesilate, a selective DA-1 receptor agonist causes systemic vasodilatation and increased renal blood flow and tubular sodium excretion. Our study aimed to evaluate the effects of high dose fenoldopam infusion on renal function during cardiopulmonary...(more)

PATIENT SAFETY IN THE NICU
2010-10-23 - English
available!

Background: Patient safety is a spearhead of the University Medical Centre of Utrecht (UMCU), the Netherlands. It recognizes that human error is inevitable. Wherever possible, the system should be (re)designed in such a way that human error is discovered or...(more)

GUIDED FAMILY-CENTERED CARE - A RANDOMIZED CONTROLLED INTERVENTIONSTUDY
2010-10-23 - English
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Giving birth prematurely and having your baby hospitalized in a neonatal intensive care unit (NICU) may cause consequences for the family lasting far beyond the hospitalization. Research shows, that parents experience stress sometimes lasting for months or years after...(more)

PRETERM BIRTH: MANAGEMENT OF MATERNAL STRESS
2010-10-23 - English
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Background: Management of stress is a very important factor of coping positive and negative life events. In this study mothers of preterm infants with different gestational age were examined in terms of their stress strategies.
Methods: The management of...(more)

\'ERGOCOACH\', CAN THEY DECLINE PHYSICAL LOAD?
2010-10-23 - English
available!

Background: Dutch law, concerning working circumstances, requires employers to take care of safety, health and welfare of their employees. In 2001 the University Medical Centres in the Netherlands had an agreement to decrease absenteeism and disability of their...(more)

CLINICAL COURSE AND PROGNOSIS AT ONE YEAR OF 1043 INFANTS BORN BEFORE 31 WEEKS AND DISCHARGED IN KANGAROO POSITION BETWEEN 2002 AND 2009
2010-10-23 - English
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Objective: Evaluate clinical course and prognosis at one year of a cohort of preterm infants cared in our ambulatory KMC program.
Design: Prospective cohort of 1043 preterm infants < 31 weeks of GA at birth discharged in kangaroo position with periodical...(more)

SEMI-STRUCTURED INTERVIEWS WITH GRIEVING PARENTS AFTER THE DEATH OF THEIR NEWBORN INFANT IN THE INTENSIVE CARE UNIT
2010-10-23 - English
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Background/aims: To obtain empiric data on parent\'s experience of death of their newborn infant and to identify variables influencing the grief reaction.
Methods: Parents of all infants who died during a 5-year-period were asked to complete a standardized...(more)

HEALTH STATUS OF CHILDREN ADOPTED FROM ETHIOPIA IN BELGIUM
2010-10-23 - English
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Aim: evaluate the demographic characteristics and health status of children adopted from Ethiopia at arrival in Belgium.
Material and Methods: retrospective review of data.
Results: 99 children (58 females, 41 males) were...(more)

BONE MINERAL DENSITY IN THE LUMBAR SPINE IN ANOREXIC GIRLS
2010-10-23 - English
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Background and aims: Cross sectional study of 161 female anorexic adolescents (14.9 ± 4.2 year).
Methods: 57/161 anorexic girls received a dual X-ray absorptiometry (DEXA) to measure their bone density. DEXA scans were performed using...(more)

THE CCC2000 BIRTH COHORT: PATTERNS OF FUNCTIONAL SOMATIC SYMPTOMS AND EATING BEHAVIOURS IN 5-7-YEAR-OLD CHILDREN
2010-10-23 - English
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Background and aims: The spectrum of functional somatic symptoms (FSS) and their relation with regulatory disturbances such as feeding/eating problems in childhood has received little attention. In this study, we analyze the prevalence of FSS and their...(more)

CHILDREN\'S BLOOD PRESSURE AND PHYSICAL ACTIVITY
2010-10-23 - English
available!

Primary prevention of cardiovascular diseases and promotion of active lifestyle should start early. Blood pressure (BP) in childhood correlates with BP in adulthood. The knowledge about children\'s physical activity influence on BP is limited.
Aims: To analyse the relation...(more)

KNOWLEDGE ABOUT CAR SAFETY SEAT USAGE IN FEMALE POPULATION IN ESKISEHIR CITY CENTER, TURKEY
2010-10-23 - English
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Objective of the study is to get data about mothers\' knowledge on car-safety seat usage with a detailed questionnaire.
Methods: A total of 1270 questionnaires were obtained from female population aged between 18 and 45 years in Eskisehir city...(more)

AUDIT ON SWINE FLU VACCINATION UPTAKE IN STAFF WORKING IN PEDIATRIC DEPARTMENT AT IPSWICH GENERAL HOSPITAL
2010-10-23 - English
available!

Background: H1N1 influenza pandemic management was the most challenging scenario faced by health authorities worldwide recently. Department of health (DOH) in UK after doing epidemiological study of first wave of swine flu (April to Sep 2009) gave recommendations...(more)

SEVERITY OF BREAKTHROUGH INFLUENZA ILLNESS AMONG CHILDREN AND ADULTS RECEIVING LIVE ATTENUATED INFLUENZA VACCINE AND TRIVALENT INACTIVATED INFLUENZA VACCINE
2010-10-23 - English
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Aims: The efficacies of live attenuated influenza vaccine (LAIV) and trivalent inactivated influenza vaccine (TIV) have been evaluated in children and adults in multiple studies; however, vaccine impact on illness severity has not been examined. This analysis...(more)

RELATIVE EFFICACY OF LIVE ATTENUATED AND INACTIVATED INFLUENZA VACCINES IN CHILDREN AS A FUNCTION OF TIME POSTVACCINATION
2010-10-23 - English
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Aims: To examine the relative efficacy of live attenuated influenza vaccine (LAIV) and trivalent inactivated influenza vaccine (TIV) as a function of time post-vaccination from three large randomized studies that compared the efficacy of LAIV and TIV in...(more)

TRENDS IN INPATIENT RSV HOSPITALIZATION (RSVH) IN YOUNG CHILDREN: AN 8-YEAR COHORT STUDY USING THE US NATIONAL HOSPITAL DISCHARGE SURVEY
2010-10-23 - English
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Aims: Examination of national trends in RSVH in infants of varying chronologic ages over an 8-year period using the US NHDS, a multistage systematic survey of inpatient hospital use.
Methods: RSVH, defined by ICD-9-CM codes 079.6 (RSV),...(more)

WHOOPING COUGH IN CHILDREN: EXPERIENCE OF HOSPITAL SÃO JOÃO (2003-2009)
2010-10-23 - English
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Background: Bordetella pertussi (BP) is a worldwide public health problem, which affects 20 to 40 million people each year.
Objective: To describe the clinical and epidemiological pattern of BP hospitalization among children.
Methods: We analyzed the clinical files of...(more)

CLINICAL SIGNS IN LATE-ONSET SEPSIS IN PRETERM NEONATES
2010-10-23 - English
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Background: Accurate diagnosis of LOS in preterm neonates is a major challenge because clinical signs are aspecific leading to unnecessary antibiotic treatment.
Aims: To determine the predictive value of clinical signs for identifying LOS in preterm...(more)

PREDICTION OF NOSOCOMIAL INFECTIONS AFTER PEDIATRIC CARDIAC SURGERY
2010-10-23 - English
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Background and aims:
Nosocomial infections are a common complication after cardiac surgery in children. Identifying patients at risk for this complication is essential to minimize postoperative morbidity and mortality. This study describes the incidence and characteristics...(more)

CARDIAC OUTPUT MONITORING: EXPERIMENTAL STUDY IN AN INFANT SHOCK ANIMAL MODEL COMPARING PULMONARY ARTERIAL THERMODILUTION, FEMORAL ARTERIAL THERMODILUTION AND BIOREACTANCE
2010-10-23 - English
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Introduction: Bioreactance, is a new non-invasive for cardiac output measurement (NICOM). We compared NICOM bioreactance to pulmonary and femoral thermodilution (PATD and FATD) in an infant shock animal model.
Methods: A prospective study was made in 9...(more)

CARDIAC OUTPUT MEASUREMENT IN JUVENILE ANIMALS WITH A SURGICALLY CONSTRUCTED EXTRA CARDIAC LEFT-TO-RIGHT SHUNT USING THE TRANSPULMONARY THERMODILUTION TECHNIQUE
2010-10-23 - English
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Introduction: Cardiac output measurement using the transpulmonary thermodilution (TPTD) technique is considered the gold standard in pediatric patients in no-shunt circulation. Goal of this study was to validate TPTD cardiac output measurement in an animal model...(more)

ASSESSMENT OF CARDIAC OUTPUT AND HEMODYNAMIC VOLUMES USING THE ULTRASOUND DILUTION TECHNIQUE IN AN ANIMAL MODEL WITH A LEFT-TO-RIGHT SHUNT
2010-10-23 - English
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Aims: To assess cardiac output and hemodynamic volumes in lambs with a left-to-right shunt using the ultrasound dilution technique (UDCO).
Methods: In 8 lambs (3.5-8.3 kg) arterial and central venous catheters were inserted and connected to the...(more)

IDENTIFICATION OF SHUNTS BASED ON THE SHAPE OF DILUTION CURVE
2010-10-23 - English
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Background and aims: The shape of dilution curve will dramatically change after indicator passes through the cardiopulmonary system in the presence of intra-cardiac shunts and a PDA. The purpose of this study was to develop an accurate algorithm for shunt...(more)

CARDIAC OUTPUT MONITORING IN CHILDREN BY BIOREACTANCE; A NEW METHOD FOR NONINVASIVE CARDIAC OUTPUT MEASUREMENT
2010-10-23 - English
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Introduction: Bioreactance, the analysis of intrabeat variations in response to high frequency transthoracic current, is a new method for noninvasive cardiac output measurement (NICOM). The objective of this study was to evaluate the cardiac index (CI) by...(more)

INTESTINAL INTUSSUSCEPTION AT COSTA RICA\'S CHILDREN\'S HOSPITAL: AN 8-YEAR STUDY
2010-10-23 - English
available!

Background and aims:

The possibility of intestinal intussusception (IS) following the introduction of rotavirus (RV) vaccines in infants is a global concern. Continuous surveillance of II cases is mandatory in these countries. The objective of this study was to describe...(more)

GASTROESOPHAGEAL REFLUX DISEASE IN INFANT: RELATIONSHIP BETWEEN MULTICHANNEL INTRALUMINAL IMPEDANCE-PH MONITORING AND CLINICAL OUTCOME
2010-10-23 - English
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Background and aims: combined multichannel intraluminal impedance and pH-monitoring (MII/pH) is a new technique identifying refluxes irrespective of acidity and detecting their duration, proximal extent and pH. These features are important when studying...(more)

COMPARISON BETWEEN ACTUAL DAILY AND RECOMMENDED NUTRIENT INTAKES, DURING THE FIRST TWO MONTHS OF LIFE, IN PRETERM ELBW INFANTS
2010-10-23 - English
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Background and Aims: Recently, the European Society of Pediatric Gastroenterology Hepatology and Nutrition has reviewed the guidelines for preterm infants\' enteral nutrition, recommending a 4.8-6.6 g/kg/day lipid intake, and a 4-4.5 g/kg/day protein intake...(more)

CALCIUM/CREATININE RATIO IN ONE URINE SAMPLE INADEQUATELY REFLECTS NORMO- AND HYPERCALCIURIA IN PRETERM BORN INFANTS
2010-10-23 - English
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Background and aims: Preterm born infants can develop nephrocalcinosis or osteopenia. The urinary calcium/creatinine ratio is frequently used to screen for these conditions.In this pilot study we investigated variations of calcium/creatinine ratios in spot...(more)

PORTAL VEIN THROMBOSIS IN NEONATES WITH UMBILICAL VASCULAR CATHETERIZATION
2010-10-23 - English
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Background: Umbilical vascular catheters are routinely inserted in critically ill newborn infants in most neonatal intensive care units (NICU). The objectives of this study were to determine catheter-associated thrombosis by color Doppler ultrasonography and...(more)

EPSTEIN-BARR VIRUS INFECTION AND GRAFT DYSFUNCTION IN THE FIRST YEAR POST-LIVER TRANSPLANTATION
2010-10-23 - English
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PERMISSIVE HYPERCAPNIA RESULTS IN A DECREASED FUNCTIONAL VESSEL DENSITY IN THE SKIN OF EXTREMELY LOW BIRTH WEIGHT INFANTS
2010-10-23 - English
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Background: Due to the increasing number of extremely low birth weight infants (ELBI) long term ventilation and its aftermath has become an important issue. One of the newer concepts for gentle ventilation is permissive hypercapnia. We were interested in the effects...(more)

THE EFFECT OF HUMAN RED CELLS STORAGE TIME ON THE MICROCIRCULATION OF PRETERM INFANTS
2010-10-23 - English
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Background: Red blood cell (RBC) transfusion practices for neonates are controversial, variable, and based on limited scientific information. To decrease donor exposure satellite packs are used leading to the transfusion of older RBCs. Transfusion of stored...(more)

THE ROLE OF ENDOTHELIAL PROGENITOR CELLS IN NEOVASCULARIZATION OF ISCHEMIC RETINA THROUGH SDF-1/CXCR4 AXIS IN OXYGEN-INDUCED RETINOPATHY RAT MODEL
2010-10-23 - English
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Retinopathy of prematurity (ROP) is still a common cause of blindness in preterm infants worldwide despite laser treatment. It is known that bone marrow derived endothelial progenitor cells (EPCs) are involved in vascular repair and neovascularization. In the present study,...(more)

NT PRO-BNP, NGAL, AND H-FABP ARE INDICATORS OF HEMODYNAMIC RELEVANCE OF PATENT DUCTUS ARTERIOSUS IN PRETERM INFANTS
2010-10-23 - English
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Background and aims: Patent ductus arteriosus (PDA) is the most common functional cardiovascular disease of preterm infants. Hemodynamic relevance for organs and circulation can neither be derived from clinical nor from echocardiographic criteria. The aim of...(more)

EARLY VERSUS SYMPTOMATIC TREATMENT FOR PATENT DUCTUS ARTERIOSUS (PDA) WITH IBUPROFEN IN PRETERM INFANTS
2010-10-23 - English
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A LOW PLATELET COUNT IS ASSOCIATED WITH TREATMENT FAILUREIN PRETERM INFANTS TREATED WITH IBUPROFEN FOR PATENT DUCTUS ARTERIOSUS (PDA)
2010-10-23 - English
available!

Background: Recent studies have demonstrated that platelet count (PLTc) and function have an important role in promoting spontaneous closure of the PDA in animal models.Aimto evaluate whether response to ibuprofen in premature infants with PDA is influenced...(more)

HYPOGLYCEMIC AGENTS SULFONYLUREAS CONSTRICT THE FETAL DUCTUS ARTERIOSUS IN THE RAT
2010-10-23 - English
available!

Background: Sulfonylureas (tolbutamide = Rastinon, glibenclamide = glyburide, glimepiride = Amaryl) inhibit K_ATP channels and induce release of insulin. In in-vitro studies, glibenclamide constricts the ductus arteriosus. Placental transport of...(more)

PERINATAL SOCIOECONOMIC AND GEOGRAPHICAL FACTORS AND RISK OF CELIAC DISEASE IN CHILDREN: A MULTILEVEL ANALYSIS OF THE SWEDISH POPULATION
2010-10-23 - English
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In Sweden, a precipitous rise in the incidence of celiac disease (CD) in children below two years of age occurred during 1985-1995. The period is well suited for investigating the socioeconomic and geographical distribution of CD in Sweden. Previous research on the...(more)

SACRAL NERVE NEUROMODULATION THERAPY; A PROMISING NEW TREATMENT FOR CHILDREN WITH REFRACTORY FUNCTIONAL CONSTIPATION
2010-10-23 - English
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Background: Sacral nerve neuromodulation (SNM) therapy has been successfully applied in adult patients with urinary and fecal incontinence. Recently, SNM therapy showed good results in adults with refractory functional constipation. No data, however, are...(more)

EFFECT OF INTRAPARTUM OXYTOCIN ADMINISTRATION ON FIRST LATCH AND BREASTFEEDING BEHAVIOUR
2010-10-23 - English
available!

Title
EFFECT OF INTRAPARTUM OXYTOCIN ADMINISTRATION ON FIRST LATCH AND BREASTFEEDING BEHAVIOUR

Authors
1.-Ana Mª Malalana Martínez; 2.-Ibone Olza Fernández; 3.-Miguel Ángel Marín Gabriel 4.- Francisco López Sánchez 5.- Modesto Durán Duque 6.- Begoña Martínez Rodríguez...(more)

BREASTFEEDING AND CHILDHOOD OVERWEIGHT
2010-10-23 - English
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Background and aims: Childhood obesity and overweight predict short and long-term morbidity as well as obesity in adulthood. Evidence is not consistent about the association of breastfeeding and childhood overweight.This study aims to evaluate the impact of breastfeeding on...(more)

PROTEIN AND ENERGY INTAKE ON DAY 4 AT THE PICU: PREDICTOR FOR OUTCOME?
2010-10-23 - English
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Background: Critically ill children are extremely vulnerable to develop malnutrition during stay on the intensive care. The aim of the study is to evaluate nutritional goals for protein and energy on day 4 of admission in relation with outcome.
Patients and...(more)

FACTORS AFFECTING RESTING ENERGY EXPENDITURE AND URINARY NITROGEN IN VENTILATED CRITICALLY ILL CHILDREN
2010-10-23 - English
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FACTORS AFFECTING RESTING ENERGY EXPENDITURE AND URINARY NITROGEN IN VENTILATED CRITICALLY ILL CHILDREN

C Jotterand2, J Depeyre2, MH Perez1, J Cotting1

1Pediatric Intensive Care Unit, University Hospital, Lausanne (CHUV),
2Department of Nutrition and Dietetics,...(more)

FREE THYROXINE LEVELS IN THE INITIAL FOUR WEEKS OF LIFE IN EXTREME PRETERM INFANTS AFFECT BRAIN GROWTH
2010-10-23 - English
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Background: Low blood thyroid hormone concentrations in the first few weeks of life in extremely preterm infants may be linked with poor neurodevelopment. We conducted a multi-centre randomised controlled trial of thyroid hormone supplementation in babies...(more)

PRETERM-BORN INFANTS PRODUCE LESS MELATONIN THAN TERM-BORN INFANTS AT 9 AND 12 MONTHS OF AGE: A RANDOMIZED CONTROLLED TRIAL
2010-10-23 - English
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Background: Melatonin production is known to be delayed in preterm-born infants up to 6 months of age. We aimed to test the profile of melatonin production in these infants at 9-12 months of age.
Methods: Twenty three term-born and 23...(more)

CELLULAR IMMUNE RESPONSE AFTER HYPOXIC ISCHEMIC BRAIN INJURY IN NEONATAL MICE PERSISTS FOR MONTHS
2010-10-23 - English
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Background and Aims: Hypoxic ischemia (HI) induces inflammation in the brain which can aggravate the damage. Immune cell infiltration into brain after hypoxic ischemia has previously been studied, but the timing and temporal interaction of these cells in the...(more)

WHOLE GENOME EXPRESSION IN VERY LOW BIRTHWEIGHT (VLBW) INFANTS WITH AND WITHOUT RETINOPATHY OF PREMATURITY (ROP) - PRELIMINARY RESULTS
2010-10-23 - English
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ASSESSMENT OF GESTATIONAL AGE IN VERY PRETERM NEONATES USING CEREBELLAR MEASUREMENTS AT CRANIAL ULTRASOUND - WHAT IS THE BEST APPROACH?
2010-10-23 - English
available!

Background and aims: Clinical assessment of gestational age (GA) can be challenging. Several ultrasound approaches to estimate GA using cerebellar measurements have been reported, claiming to be simpler and more accurate than clinical assessment. We compare...(more)

CONTRIBUTION OF CONGENITAL ANOMALIES TO PRETERM BIRTH RISK IN THE NETHERLANDS
2010-10-23 - English
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Objective: To asses the extents to which congenital anomalies affect risk of preterm birth.
Methods: For the present study, we analysed data on 1,972,058 newborns registered in the Netherlands Perinatal Registry database (inclusion criteria 16...(more)

RISK FACTORS FOR CONGENITAL ANOMALIES IN THE NETHERLANDS
2010-10-23 - English
available!

Objectives: To determine the relation between several potential risk factors and the risk of having a newborn with one or more congenital anomalies.
Participants: Data on 1,594,380 registered newborns from the Netherlands Perinatal Registry...(more)

IRREGULAR MENSTRUAL CYCLE, OBESITY AND PRETERM BIRTH
2010-10-23 - English
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Background and aims: Obesity and pre-pregnancy irregular menstrual cycle may independently increase the risk of preterm birth. High body mass index (BMI) and irregular menstrual cycle are both symptoms of the polycystic ovary syndrome (PCOS). The endocrine...(more)

USE OF A RESPIRATORY FUNCTION MONITOR DURING POSITIVE PRESSURE VENTILATION IN THE DELIVERY ROOM - A RANDOMIZED TRIAL
2010-10-23 - English
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Background and aims: International guidelines recommend that positive pressure ventilation (PPV) in the delivery room (DR) is guided by chest rise and heart rate. Tidal volume (V_T) delivery during resuscitation is highly variable and we have shown...(more)

HIGH-SPEED VIDEO ANALYSIS OF HIGH-AMPLITUDE BUBBLE-CONTINUOUS POSITIVE AIRWAY PRESSURE DEMONSTRATES THAT âWATER HAMMERâ EFFECTS CAUSE LARGE OSCILLATIONS IN AIRWAY PRESSURE
2010-10-23 - English
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Background and aims: We have shown, in lavaged rabbits, that High-Amplitude Bubble-Continuous Positive Airway Pressure (HAB-CPAP,see figure) provides greater gas exchange and lower work of breathing than conventional bubble-CPAP (PedsResearch,June,2010). The...(more)

EFFICIENCY OF MASK VENTILATION IN PRETERM INFANTS AT BIRTH
2010-10-23 - English
available!

Aim: To investigate the efficiency of mask ventilation in preterm infants after birth.
Methods: Recordings of airway pressures and gas flow of infants < 32 weeks gestation needing mask ventilation at birth were reviewed. Respiratory support...(more)

INHALED NITRIC OXIDE AFTER OXIDATIVE STRESS IN NEWBORN RATS. EFFECTS ON VEGF EXPRESSION AND ALVEOLARIZATION
2010-10-23 - English
available!

Background and aims: Exposure of newborn rats to hyperoxia decreases VEGF expression and impairs alveolarization. Much evidence indicates that NO plays a role in VEGF signaling and recent studies have shown that NO induces VEGF synthesis. The purpose of this...(more)

PRENATAL MATERNAL STEROID TREATMENT - EFFECT ON MORTALITY AND BRONCHOPULMONARY DYSPLASIA (BPD) IN EXTREMELY PREMATURE INFANTS
2010-10-23 - English
available!

Background and aims: Prenatal steroids (PS) are considered important in the treatment of extremely premature infants. The study was undertaken to evaluate the impact of PS on mortality and BPD in a national cohort with a high rate of prenatal steroid...(more)

TIMING OF SURFACTANT TREATMENT IN EXTREMELY PREMATURE INFANTS - EFFECTS ON MORTALITY AND DEVELOPMENT OF BRONCHOPULMONARY DYSPLASIA (BPD)
2010-10-23 - English
available!

Background and aims: The effect of early surfactant treatment is uncertain. The aim of this study was to evaluate mortality and moderate/severe BPD in relation to timing of surfactant treatment.
Methods: All 452 admitted infants with...(more)

PROBIOTICS SUPPLEMENTATION INCREASES INTESTINAL BLOOD FLOW IN EXTREMELY LOW BIRTH WEIGHT (ELBW) NEONATES
2010-10-23 - English
available!

Background: Proposed benefits of probiotics supplementation are multiple; recently, vasoactive properties of trace amines, produced by probiotics, have been shown to affect mesenteric vasculature in animal models. The effects of probiotics on intestinal blood...(more)

GROWTH OF INFANT FED STARTER FORMULA CONTAINING PREBIOTICS OR SYMBIOTIC
2010-10-23 - English
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Objective: To assess growth of infants fed starter formula supplemented with either prebiotics or symbiotic. In addition, gut microbiota was studied.
Methods: Healthy, full term newborns (n= 240) were enrolled before the 14^th day of their life...(more)

INFLUENCE OF NUTRITIONAL STATUS AT 36 WEEKS POSTMENSTRUAL AGE ON BODY COMPOSITION OF VLBW INFANTS ON THE FIRST TWO YEARS
2010-10-23 - English
available!

Objective: Compare body composition in the first two years between undernourished Very Low Birth Weight Infants (UNVLBWI) , adequately nourished (AN) VLBWI and term infants (T).
Methods: Cohort study of 95 VLBWI, < 34weeks GA, classified at 36weeks PMA as...(more)

LONG-COURSE, BUT NOT SHORT-COURSE, DEXAMETHASONE TREATMENT IN ELBW INFANTS RESULTS IN HIGHER INTELLECTUAL IMPAIRMENT RATES AT PRESCHOOL AGE
2010-10-23 - English
available!

EFFECT OF OMT ON LENGTH OF STAY AND WEIGHT GAIN IN A POPULATION OF PRETERM INFANTS
2010-10-23 - English
available!

Background and aims: The use of osteopathic manipulative treatment (OMT) in preterm infants has been documented and results from previous studies suggest the association between OMT and length of stay (LOS) reduction, as well as significant improvement in...(more)

RESPIRATORY SYNCYTIAL VIRUS HOSPITALIZATION IN INFANTS WITH CHRONIC LUNG DISEASE: AN 8-YEAR RETROSPECTIVE NATIONAL HOSPITAL SURVEY
2010-10-23 - English
available!

Aims: To determine trends in proportions of respiratory syncytial virus hospitalization (RSVH) over an 8-year time period beginning in 1998 when palivizumab was licensed in the United States using a retrospective cohort study of all hospitalized children < 2...(more)

MORTALITY AND CAUSES OF DEATH IN CHILDREN REFERRED TO A TERTIARY REFERRAL EPILEPSY CENTER
2010-10-23 - English
available!

Purpose: To describe causes of death in children with difficult to treat epilepsy.
Methode: 3030 children aged 1 month to 18 years were referred to admission or outpatient visit to Dianalund Epilepsy Center from 1/1 99 to 31/8 2008. From the...(more)

PASSIVE DISTRACTION IS THE ONLY DETERMINANT OF PAIN DURING VENOUS BLOOD SAMPLING IN SCHOOL CHILDREN IN AN OUTPATIENT CLINIC SETTING
2010-10-23 - English
available!

Introduction: Non-pharmacological interventions can be used to minimize discomfort, but data on the impact of non-pharmacological interventions on procedural pain in children are limited. We therefore evaluated the impact of distraction (TV watching) during elective...(more)

A search for the \"Holy Grail\" in the evaluation of febrile neonates aged 28 days or less: A prospective study
2010-10-23 - English
available!

Objective: To prospectively determine the reliability of low-risk criteria to exclude serious bacterial infection (SBI) in febrile neonates aged ?28 days.
Patients and methods: All febrile neonates aged ?28 days who were hospitalized...(more)

AUTISM SPECTRUM (ASD) AND ATTENTION DEFICIT HYPERACTIVITY (ADHD) DISORDERS EPIDEMICS: DOES FETAL EXPOSURE TO ENDOCRINE DISRUPTING CHEMICALS PLAY A ROLE?
2010-10-23 - English
available!

Background: The prevalence of neurodevelopmental disorders, such as ASD and ADHD, is increasing. This might at least partly be explained by an increased awareness of symptoms and a shift in diagnosis. However, further studies of the incidence of ASD and ADHD are...(more)

INFLUENCE OF IQ/DQ ON OUTCOME IN CHILDHOOD EPILEPSY SURGERY
2010-10-23 - English
available!

Purpose: Operations of children with intellectual disabilities have been questioned by some because of suspicion of a poor outcome.
Methods/material: Retrospective study of all Danish children (n=65) operated between 1996 and 2007. 25 children had an...(more)

INTEGRATING TRADITIONAL CHINESE MEDICINE INTO PRIMARY CARE PRACTICE
2010-10-23 - English

Background: Complimentary and Alternative Medicine (CAM) is used by millions of people to supplement Western medicine practices or in some cultures, substitute for Western medicine. It is imperative that pediatric nurses be knowledgeable concerning health beliefs and...(more)

MAKING A DIFFERENCE: INTRODUCING PAEDIATRIC CRITICAL CARE OUTREACH SUPPORTS EFFECTIVENESS OF AN EARLY WARNING SCORING SYSTEM IMPROVING PATIENT SAFETY
2010-10-23 - English

Nottingham Children\'s Hospital has recently developed and introduced an integrated Paediatric Early Warning Scoring tool and Observation Chart. To support this development and to enable the structured escalation plan to be instigated, a PCCOT team was also introduced and...(more)

SECOND COURSE OF IBUPROFEN FOR PDA : COMPARISON OF 10-5-5 'VS' 20-10-10 MG/KG IN INBORN INFANTS < 28 WKS GA
2010-10-23 - English

Background and aims: Recent pharmacological data suggest increased ibuprofen doses for treating patent ductus arteriosus (PDA). We evaluated the effectiveness and tolerance of a double dosed second ibuprofen course in our population.
Methods:...(more)

Panel Discussion
2010-10-22 - English

CHILDREN, DISASTERS AND RESILIENCE
2010-10-22 - English

Pediatric Disaster Preparedness and Response
2010-10-22 - English

Pediatric Disaster Preparedness and Response
2010-10-22 - English

CYCLOSPORINE AND REGIONAL HEMODYNAMICS OF NEWBORN PIGLETS FOLLOWING ASPHYXIA-REOXYGENATION: A DOSE-RESPONSE STUDY
2010-10-04 - English
available!

Introduction:
Asphyxiated neonates commonly have multi-organ failure. Cyclosporine has recently been shown to improve systemic hemodynamics, however, its effects on the regional circulation have not yet been studied. We hypothesize that cyclosporine in asphyxiated newborn...(more)

Branched Chain Amino Acid Requirements for Term Neonates
2010-10-25 - English
to be announced!

F. Maingay-de Groof(1), L. Huang(1), G.J. Voortman(1), C. Chao(2), Y. Huang(2), J.B. van Goudoever(1)
(1)Neonatology, Pediatrics, Erasmus MC Sophia, Rotterdam, The Netherlands, (2)Neonatology, Pediatrics, Fudan Children\'s Hospital, Shanghai, China

Background:...(more)

Prenatal and perinatal behaviour
2010-10-25 - English
to be announced!

Brain Plasticity After Preterm Birth: A FMRI Study of the Visual Pathway
2010-10-23 - English
to be announced!

R. Ha-Vinh Leuchter(1,2), T. Chaminade(3), V. Millet(1), C. Deruelle(3)
(1)Médecine Néonatale, Assistance Publique-Hôpitaux de Marseille, Marseille, France, (2)Hôpital des Enfants, HUG, Geneva, Switzerland, (3)Institut de Neurosciences Cognitives de la Méditeranée,...(more)

Regional Cortical Surface Area Relates to IQ in Young Adults Born Preterm with Very Low Birth Weight (VLBW)
2010-10-23 - English
to be announced!

J. Skranes(1,2,3), G.C. L

Innate Antibiotics
2010-10-23 - English
to be announced!

A Randomized, Doubleblind Crossover Study Comparing RHBSSL (Recombinant Human Bilesaltstimulated Lipase) and Placebo Added to Infant Formula in Preterm Infants
2010-10-05 - English
to be announced!

PERSISTENCE OF IMMUNE RESPONSE TO CANDIDATE MENINGOCOCCAL SEROGROUPS A,C,W-135,Y TETANUS TOXOID-CONJUGATED VACCINE (MENACWY-TT) UP TO 42 MONTHS FOLLOWING PRIMARY VACCINATION
2010-10-04 - English
to be announced!

Background and aims: A primary dose of the candidate meningococcal A,C,W-135,Y tetanus toxoid-conjugated vaccine (MenACWY-TT) was immunogenic and well tolerated in subjects aged 15-19 years (NCT00126945). Here, the persistence of the immune response to...(more)