Infections of the peripheral system: Lyme disease & AIDS
Petach Tikva, Israel
40 slide(s) – 00:23:23– English –2010-09-26
Lyme disease is a systemic infection due to the tick-borne spirocheta Borrelia burgdorferi associated with musculoskeletal, neurological and cardiacmanifestations. It is endemic in the northeast, upper Midwest and northern California and Oregon of the United States as well as in forested regions in Europe.There is continuous rise in incidence and progress has been made with disease prevention by increased public education to reduce exposure risk, promotion of early diagnosis and effective therapy. The neurological symptomatology is mainly that of peripheral nervous system (PNS) involvement, and delineation of presentation and course of PNS abnormalities in Lyme diseasemay foster early diagnosis and therapy. Neuromuscular disorders are common in human immunodeficiency virus (HIV) infection, occur at all stages of disease and affect all parts of the PNS. They are due to HIV itself, immune suppression and dysregulation, opportunistic infections, associated disorders and side effects ofmedications. Understanding the differential diagnosis and workup of distal symmetric polyneuropathy; inflammatory demyelinating polyneuropathy; mononeuropathy; mononeuropathy multiplex; autonomic neuropathy and progressive polyradiculopathy in HIV carriers and AIDS patients is mandatory for accurate diagnosis and therapy.