12th Congress of the European Hematology Association
Dr. M. Sadelain

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Biography
New York, United States of America  
Memorial Sloan-Kettering Cancer Center

Michel Sadelain, MD, PhD, is a Member of the Department of Medicine and the Molecular Pharmacology Program at Memorial Sloan-Kettering Cancer Center, as well as the director of the Cell Engineering Center at the Sloan-Kettering Institute and a Professor of Medicine at Cornell University. After obtaining his medical degree from the University of Paris and his PhD from the University of Alberta, he began working on gene transfer at the Whitehead Institute at MIT before joining the MSKCC faculty in 1994. His group was the first to demonstrate the feasibility of treating [beta]-thalassemia by transferring the human [beta]-globin gene in bone marrow cells of mice suffering from [beta]-thalassemia (May et al., Nature, 2000). His laboratory next demonstrated that adult [beta]0-thalassemia could be rescued by lentiviral-mediated transfer of the human [beta]-globin gene (Rivella, Blood, 2003), paving the way for clinical studies that are currently in preparation. His other work deals with the treatment of leukemia and other cancers, also using gene transfer as the basis for enhancing the function of patient cells.

Presentations by Dr. M. Sadelain currently available on MultiWebcast.com
12th Congress of the European Hematology Association

Globin gene transfer for red blood cell disorders, a paradigm for stem cell-based gene therapy
2007-06-09 - English - Hemoglobinopathies