Many problems such as non-response, pharmacokinetic interactions with clinical consequences and adverse effects (pharmacovigilance) may be observed in patients submitted to psychopharmacotherapy. These risks are increased in patients belonging to the category of “special...(more)
A widely introduced pharmacokinetic test in psychopharmacotherapy is therapeutic drug monitoring (TDM). It is especially recommended in patients who are non-compliant, who poorly tolerate, or who do not respond to a medication. It is also useful in patients belonging to the...(more)
D. Cohen1, H. Burger2, C. Gispen de Wied3, R. Stolk1, D. Grobbee4 1Clinical Epidemiology, University of Groningen, 2Interdisciplinary Center for Psychiatric Epidemiology, University...(more)
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