Disclosure : Andrea Mike is a recipient of the 2008 McDonald Fellowship from the Multiple Sclerosis International Federation. This study was supported by the Hungarian National Research Fund (OTKA K77892), the Hungarian Neuroimaging Foundation (both to Zsolt Illes), EEA/Norwegian Financial Mechanism HU 0114 – “Save what can be saved” – applied neurological research using high-field magnetic resonance imaging (to the Diagnostic Center of Pecs) and the National Multiple Sclerosis Society (Grant RG3574A1) (to Charles RG Guttmann).