The socioeconomic consequences of optic neuritis: a controlled national study
Disclosure : The study is a part of a larger study supported by the Center of Healthy Aging, Faculty of Health Sciences, University of Copenhagen with the purpose of identifying the burden of neurological diseases. Furthermore the study is part of European Brain Network evaluating the Cost of Disorders of the brain in Europe 2010. None of the founding had any influence in study design; in the collection, analysis and interpretation of data; in the writing of the report; and in the decision to submit the paper for publication.
There are no conflicts of interests among the authors.
9 slide(s) – English – 2011-09-10
Optic neuritis (ON) often precede multiple sclerosis (MS) which causes negative effects on health-, and social- issues for the patients and society, thus causing significant socioeconomic burden. The burden of ON with and without MS, before and after a diagnoses has however never been established.
Using all national records from the Danish National Patient Registry (1998-2006), we identified 1677 patients with ON and compared with 6708 randomly age-, sex- and geographic matched citizens. Direct costs included frequencies and costs of hospitalizations and weighted outpatient use, frequencies of visits and hospitalizations and costs from primary sectors, and the use and costs of drugs. Indirect costs included labor supply; income data. All social transfer payments were also calculated.
Patients with ON had significantly higher rates of health-related contact and medication use and very low employment rate which incurred a higher socioeconomic cost and lower income level of employed patients than of control subjects. The annual total excess direct and indirect costs relative to matched controls were €3501 for ON pts and €9215 for pts with a diagnose of ON and MS combined. The ON and ON+MS pts received an annual mean excess social transfer income of €1175 and €4619. ON/ON+MS pts presented social and economical consequences up to eight years before diagnose, and this increased after the diagnosis was established.
ON especially if combined with a diagnose of MS causes socioeconomic consequences for the individual patient and for society. Indirect costs are a far more important economic factor.