15th Congress of the European Federation of Neurological Societies
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Assoc. Prof. Graham Barrett

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Assoc. Prof. Graham Barrett, Australia  

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15th Congress of the European Federation of Neurological Societies

Rescue of spatial memory in Alzheimer s disease mice by knockdown of the p75 neurotrophin receptor
2011-09-10 - English - Poster Session 1: Ageing and dementia 1

We proposed that downregulation of the p75 neurotrophin receptor (p75), a receptor that promotes atrophy and apoptosis of cholinergic neurons, may improve cognitive performance in Alzheimer’s model mice. We compared spatial learning in 14-month-old Tg2576 mice to Tg2576...(more)