Prevalence of endometrial cancer in symptomatic post menopausal women with thickened endometrium
Dr. Maheswari Srinivasan
Birmingham, United Kingdom
11 slide(s) – English – 2012-03-28
1) To ascertain the pickup rate of endometrial cancer in women attended the post-menopausal bleeding clinic with Postmenopausal bleeding and thickened endometrium.
2) To ascertain the prevalence of other pathology (polyps) in the same cohort of women
Materials and Methods-
Retrospective review of the case notes of women who attended with symptoms of post menopausal bleeding over 3 year period from Jan 2008 until dec 2010. 262 patients were identified and analysed, 13 were HRT users, 16 were on Tamoxifen
There were 56 clinics and 262 women attended
101 women had thickened endometrium ET > 4 mm. Endometrial pipelle samples and further investigations were carried out in these women. Ten women were diagnosed with endometrial cancer (10%) and three women had cervical cancer. Seven women were diagnosed with complex hyperplasia in the initial pipelle sample, of which endometrial cancer was present in 4 women.
21 patient had sonographic findings suggestive of endometrial polyp of which 12 confirmed by the gold standard (hysteroscopy) (57%)
Conclusion- 10% of women with thickened endometrium turned out to have endometrial cancer this correlates to the international observational studies.
No cancer cases found in the cohort that had ET<4mm.