9th European Congress on Menopause and Andropause
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Prevalence of endometrial cancer in symptomatic post menopausal women with thickened endometrium

Dr. Maheswari Srinivasan
Dr. Maheswari Srinivasan
Birmingham, United Kingdom  
11 slide(s) – English – 2012-03-28
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Aim-
1) To ascertain the pickup rate of endometrial cancer in women attended the post-menopausal bleeding clinic with Postmenopausal bleeding and thickened endometrium.
2) To ascertain the prevalence of other pathology (polyps) in the same cohort of women


Materials and Methods-
Retrospective review of the case notes of women who attended with symptoms of post menopausal bleeding over 3 year period from Jan 2008 until dec 2010. 262 patients were identified and analysed, 13 were HRT users, 16 were on Tamoxifen

Results-
There were 56 clinics and 262 women attended
101 women had thickened endometrium ET > 4 mm. Endometrial pipelle samples and further investigations were carried out in these women. Ten women were diagnosed with endometrial cancer (10%) and three women had cervical cancer. Seven women were diagnosed with complex hyperplasia in the initial pipelle sample, of which endometrial cancer was present in 4 women.
21 patient had sonographic findings suggestive of endometrial polyp of which 12 confirmed by the gold standard (hysteroscopy) (57%)

Conclusion- 10% of women with thickened endometrium turned out to have endometrial cancer this correlates to the international observational studies.
No cancer cases found in the cohort that had ET<4mm.
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