BACKGROUND: Most of women who reach menopause develop menopausal symptoms, primarily hot flashes. Hormone replacement therapy (HRT) was considered as the first-line treatment for vasomotor symptoms but, consumption of these products may have gastrointestinal side effects, hirsutism, weight gain and vaginal bleeding. Also, they increase the risk of endometrial, breast and ovary cancers in long term use. Despite the fact that there is limited scientific evidence describing efficacy and long-term safety of herbal products, many women use them to relief menopausal symptoms.
Methods: This paper reviews the effect of Phytoestrogens commonly used in menopause such as trigonella foenum-graecum on hot flash. We searched the MEDLINE database from 2000 to September 2011 about the effect of herbal supplementation on relief of hot flash.
Results & conclusion: The evidence to date suggests that trigonella foenum-graecum is safe and effective for reducing hot flash. It can reduce the number and strength of the vasomotor symptoms. Other Phytoestrogens extracts, including soy foods and red clover have a positive effect on menopausal symptoms as hot flash but their efficiency is minimal, whereas they have positive health effects on plasma lipid concentrations and may reduce heart disease. So our study suggests more study should be done about herbal supplementation, their safety and efficiency.
Key words: menopause, fenugreek, hot flash
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