PHARMACEUTICAL TREATMENT OF STRESS URINARY INCONTINENCE AND DEPRESSION AT POST MENOPAUSAL WOMEN WITH DULOXETINE MEDICATION.
Dimitrakopoulos Spyridon, Andriotis Antonios, Koliantzaki Sofia, Sidiropoulou Anna, Saltamavros Alexandros, Sorras Konstantinos, Tsokaki Theodora, Karachaliou Euthimia, Papadimitriou Dimitrios, Sidiropoulos Nikolaos.
General Hospital of Pyrgos, Obstetric-Gynecology Department, Pyrgos, Greece.
AIM: Is to consider the positive action of Duloxetine at the stress urinary incontinence and depression at post menopausal women.
MATERIAL - METHOD: Our study was consisted of 40 women (48-82 year old), menopausal at least 1 year, with increase of gonadotrophins. They were examined psychiatrically and were classified as depressive according to the DSM IV standards. During the study was done biochemical control, record of vital signs and urodynamic control. Was medicated 20 mg/d for 1w and 40mg Χ 2/d for 24w. The progress of the patients was evaluated at 4w, 12w and 24w physical according to anonymous questionnaire of depression (Beck scale) and clinical with urodynamic control and count of the incontinence episodes. Statistical analysis became with method SPSS (prices p>0,001 were considered statistically not important).
RESULTS: The depression and stress incontinence of the post menopausal women presented statistical insignificant progress. Duloxetine was proved to be effective at the elderly patients with recurrent important depressive disorder. Duloxetine is less effective for the stress urinary incontinence at post menopausal women against other medicines.
CONCLUSION: The medication of Duloxetine isn\'t effective alternative treatment for the old post menopausal women with depression and stress urinary incontinence.
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