ARE THE MORE NUMBER OF PELVIC NODES REMOVED INCREASE THE INCIDENCE OF POSITIVE NODE AND SURVIVAL IN CERVICAL CANCER PATIENTS?
Assoc. Prof. Prapaporn Suprasert
Disclosure : We would like to thank the National Research University Project under Thailand’s Office of Higher Education Commission and Chiang Mai University for the financial support
13 slide(s) – English – 2011-09-11
Background & Aim:
The relation between the number of removed node and the incidence of positive node in cervical cancer patients treated with radical hysterectomy and pelvic lymphadenectomy (RHPL) did not mention in the prior reports. Moreover, the association of the more number of removed node and the survival still debate. To examine this relationship, we conduct this retrospective study to identify the relationship of the number of removed pelvic nodes and the incidence of positive node as well as the 5-year disease-free survival (DFS).
Methods: Medical record of 843 cervical cancer patients undergoing RHPL at Chiang Mai university hospital between January 2002 and December 2008 were reviewed. The number of removal nodes were divided into 4 groups as follow; group I= < 20 nodes (N=259), group II = 21-30 nodes (N=344), group III =31-40 nodes (N=171) and group IV = > 41 nodes (N =69). The incidence of positive node and 5-year DFS of patients in each groups were compared.
Result: The incidence of positive pelvic nodes was highest in group I (23.2%), followed by group III (14.0%), group II (14.2%) and group IV (10.1%). The recurrence rate and 5 year DFS were not significantly different among the groups. If patients with and without nodal involvement were considered separately, the 5-year DFS in all groups were also not significantly different.
Conclusion: The higher number of removed pelvic node was not related to the incidence of positive node and 5-year DFS.