IMPROVED 8-YEARS SURVIVAL FOR OVARIAN CANCER PATIENTS FIGO STAGE IIIC OPERATED AT TEACHING HOSPITALS IN NORWAY
Oslo, Norway 
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9 slide(s) – English – 1999-11-30
IMPROVED 8-YEARS SURVIVAL FOR OVARIAN CANCER PATIENTS FIGO STAGE IIIC OPERATED AT TEACHING HOSPITALS IN NORWAY
Szczesny W1,2, Paulsen T2,3, Tropé C2,4
1Sykehuset -Innlandet Hospital Trust, Dept. of Gynecology and Obstetrics, Elverum; 2Cancer Registry of Norway; 3 Oslo University Hospital, Dept. of Gynecological Cancer/Norwegian Radiumhospital; 4 Department Group of Clinical Medicine, Faculty of Medicine, University of Oslo, Norway
Bacground and Aims. Paulsen et al. (1), has previously shown short-term survival benefit for patients being operated at Teaching Hospitals (THs) in Norway compared to those operated at Non-Teaching Hospitals (NTHs).
The aim of this study was to assess prognostic factors that promote long-term survival among patients operated for advanced ovarian cancer at THs compared to NTHs in Norway. Materials and methods. Data from Cancer Registry of Norway (OVANOR) on 198 patients with advanced invasive ovarian, tubal and peritoneal cancer (EOC) FIGO stage IIIC was extracted. The main outcome was overall survival (OS) in months. Results: Observation time was 8 years (7.8-8.7). Patients operated primarily at THs (n=108) had better median OS (32 months vs. 23 months, p=0,04) compared to patients operated at NTHs (n=90). Survival-rate was 15% (15women) vs. 10% (8women) in favor of THs at the end of follow-up. There were identified several prognostic factors for OS (optimal surgery*, residual disease 0cm, neoadjuvant chemotherapy and, tumor-differentiation grade). After adjustment for three prognostic factors (optimal surgery, neoadjuvant chemotherapy, tumor-differentiation grade), the risk of death within 8 years at NTH compared to TH was unchanged, hazard ratio 1.43 CI [1.02-1.99]. We found a difference in poor performance status between patients in TH-group (N=7, [7%]) versus NTH (N=23 [26%]) with better OS at TH (Tbl.1). However, the groups were too small to be used as a prognostic factor in analysis. Conclusion: EOC FIGO III patients operated at THs in Norway have improved long-term survival compared to patients operated at NTHs.
*Hysterectomy, BSO, Omentectomy
1) Paulsen T, Kjaerheim K, Kaern J, Tretli S, Tropé C. Improved short-term survival for advanced ovarian, tubal, and peritoneal cancer patients operated at teaching hospitals Int J Gynecol Cancer.2006 Jan-Feb;16 Suppl 1:11-7.
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