ESH Eleventh International Conference
Webcasted Presentations

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Opening Session3 presentations / courses
Welcome
by Josy Reiffers
to be announced!
Welcome
by John Goldman
2009-09-11 6 minutes  
ICMLF Inaugural Lecture - TKIs now but what next?
by Brian Druker
2009-09-11 21 minutes    
 
Activated kinases in MPDs3 presentations / courses
TET2 alterations in the multistep onset of myeloproliferative disorders
by Francois Delhommeau
2009-09-11 10 minutes    
Point mutations in PDGFRA in myeloproliferative disease
by Steffen Koschmieder
2009-09-11 8 minutes    
Jak2 regulates Bcr-Abl signaling
by Ralph Arlinghaus
to be announced! (Waiting for speaker approval)
 
Molecular events in CP4 presentations / courses
Which molecular events are really 'initiating?'
by Michael Deininger
2009-09-11 19 minutes  
The Myb gene in leukemogenesis
by Alan Gewirtz
to be announced! (Waiting for speaker approval)
CHIP works with Hsc-70 co-chaperone to degrade BCR-ABL
by Yoshiro Maru
2009-09-11 6 minutes  
Blockage of GSK3b promotes sensitivity of Ph+ LSC to Bcr-Abl inhibition
by carlo gambacorti
2009-09-11 11 minutes  
Molecular events in advanced phase4 presentations / courses
Which molecular events really underlie progression?
by Danilo Perrotti
2009-09-11 18 minutes  
Loss of miR-328 may promote progression from CP to AP
by Anna Eiring
to be announced! (Waiting for speaker approval)
Genetic alterations in high-risk, "BCR-ABL1-like" ALL
by Charles Mullighan
2009-09-11 13 minutes    
Whole genome sequencing of Ph-positive ALL
by Ilaria Iacobucci
2009-09-11 10 minutes    
Genomic instability5 presentations / courses
The B cell mutator AID promotes B lymphoid blast crisis in CML
by Markus Müschen
2009-09-11 12 minutes  
Mitochondrial origin of intracellular ROS in CML
by Martin Sattler
2009-09-11 8 minutes    
Hematopoietic stem cell quiescence promotes error prone DNA repair and mutage...
by Emmanuelle Passegue
2009-09-11 18 minutes  
Alternatives NHEJ is a novel therapeutic target in a subset of imatinib resis...
by Feyruz Rassool
2009-09-11 11 minutes    
Results of SNP-arrays in various phases
by Simona Soverini
2009-09-11 11 minutes    
 
Leukemia stem cells4 presentations / courses
Defining and targeting LSC
by Tessa Holyoake
2009-09-11 15 minutes    
Effects of IFNa on LSC
by Marieke Essers
2009-09-11 10 minutes    
Smo inhibition to eradicate LSC
by G. Martinelli
2009-09-11 12 minutes  
Targeting CML stem/progenitor cells by combining new ABL and JAK inhibitors
by Xiaoyan Jiang
2009-09-11 7 minutes  
Plenary presentation1 presentation / course
The real role of JAK2-V617F
by Tony Green
2008-00-00 13 minutes  
 
Animal models3 presentations / courses
Can murine models still be improved?
by Rick van Etten
2009-09-12 21 minutes  
Generation of an in vivo BCR-ABL T315I embryonic stem cell
by Michael Melkus
2009-09-12 11 minutes  
Novel molecular pathways in LSC using mouse models
by Shaoguang Li
2009-09-12 16 minutes  
 
Immunobiology4 presentations / courses
How and when to use immunotherapy?
by Richard Clark
2009-09-12 20 minutes  
Effect of TKIs on 'normal' immune responses
by Katayoun Rezvani
2009-09-12 11 minutes  
Expansion of functional pre-existing memory T-cells during TKI treatment
by Satu Mustjoki
2009-09-12 12 minutes  
Ex vivo expanded NK cells to target quiescent LSC
by Agnes Yong
2009-09-12 10 minutes  
Which mechanisms are important?
by Andreas Hochhaus
to be announced! (Waiting for speaker approval)
FoxO involvement in CML
by Daniela Cilloni
2009-09-12 12 minutes    
MDR polymorphisms
by Jan Cornelissen
to be announced! (Waiting for speaker approval)
Glucocorticoid induced leucine zipper overcomes TKI resistance
by Bruno Quesnel
2009-09-12 11 minutes    
Resistance profile of bosutinib using a high throughput sequencing assay
by Rocco Piazza
2009-09-12 7 minutes    
Plk1 as a novel target in CML: overriding TKI resistance with a Plk1 inhibitor
by Karoline Gleixner
to be announced!
Combination therapy and mechanism of resistance to the combined BCR-ABL and p...
by Stefan Balabanov
to be announced! (Waiting for speaker approval)
 
Clinical results of TKIs6 presentations / courses
Future prospects
by Tim Hughes
2009-09-12 17 minutes    
IM plus pegylated INF-α
by Delphine Réa
2009-09-12 9 minutes  
KD mutations during second line TKI therapy
by Susan Branford
to be announced! (Waiting for speaker approval)
Factors determining an optimal molecular response
by David Marin
2009-09-12 11 minutes  
Imatinib longterm effects study in CML
by carlo gambacorti
2009-09-12 9 minutes  
STIM update
by François-Xavier Mahon
2009-09-12 9 minutes  
New therapeutic approaches6 presentations / courses
Targeting BCL6 in lymphoid blast crisis CML
by Markus Müschen
to be announced! (Waiting for speaker approval)
Where next?
by Jorge Cortes
2009-09-13 18 minutes  
Front-line use of dasatinib and nilotinib
by Gianantonio Rosti
2009-09-13 13 minutes    
A new inhibitor of T315I
by Jim Griffin
to be announced! (Waiting for speaker approval)
Forskolin of FTY720 for CML in advanced phase
by Danilo Perrotti
2009-09-13 14 minutes  
Inhibiting autophagy in CML therapy
by Paolo Salomoni
2009-09-13 11 minutes    
The next decade5 presentations / courses
DEBATE: Do we need to target quiescent stem cells? (FOR)
by Tessa Holyoake
2009-09-13 10 minutes  
DEBATE: Do we need to target quiescent stem cells? (AGAINST)
by John Goldman
2009-09-13 11 minutes  
DEBATE: Do we need monitoring for FISH-negative patients? (FOR)
by Giuseppe Saglio
2009-09-13 18 minutes    
DEBATE: Do we need monitoring for FISH-negative patients? (AGAINST)
by Charles Schiffer
2009-09-13 15 minutes    
What does the future hold?
by John Goldman
2009-09-13 8 minutes