PEDIATRIC PARAPNEUMONIC EMPYEMA EPIDEMIOLOGY IN SOUTHERN SPAIN (2005-2009)
Spain 
8 slide(s) – English – 1999-11-30
PEDIATRIC PARAPNEUMONIC EMPYEMA EPIDEMIOLOGY IN SOUTHERN SPAIN (2005-2009)
Author(s):
S.C. Lovillo, D.F. Neyra, D.M. Castillo, B.C. Santander, J.A.L. Leal, A. Porras, I.O. Santaella
Institute(s):
Pediatrics Infectious Disease, Universitary Hospital Virgen del Rocio, Sevilla, Spain
Text:
Objetive: to describe pediatric parapneumonic empyema(PPE) epidemiology in the previous years to the introduction of the new generation of conjugate pneumococcal vaccines (10 and 13-valent)
Methods: All patients < 14 years old admitted to a tertiary pediatric hospital with a diagnosis of PPE were prospectively enrolled from January 2005 through December 2009
Patients: Overall 219 patients had PPE. Incidence rates for PEE remained stable during the study period with a non statistically significant increase in 2009 (p=0.08 for comparison with 2005). There was a significant higher frequency of PPE cases in the last quarter of 2009 compared to historical data for the same term in previous four years (p=0.001),coincidental with increasing circulation of 2009 pandemic influenza A (H1N1) in our population. Median age and duration of symptoms prior to admission were 44 months (intercuartilic range 32-70 m) and 4 days (intercuartilic range 3-6 days), respectively. Nearly a third (30%) of patients were admitted to ICU. There were no fatalities. A microorganism was isolated from blood and/or pleural fluid cultures in 21% PPE cases. Pneumococci were detected in 72% of culture-positive and 79% culture-negative samples. Serotypes were determined for 104 PPE cases; serotype 1 was the most prevalent serotype identified (42%) followed by serotypes 7F (20%), 3 (16%), 19A (8%) y 5 (7%).
Conclusion: Pneumococcal serotype 1 remained the most common cause of PPE cases over the last 5 year period. Continued enhaced surveillance is essential to monitor impact of new generation of pneumococcal conjugate vaccines in PPE epidemiology.
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