HIV CHARACTERISTICS AND EDUCATIONAL ACHIEVEMENT OF A COHORT OF HIV INFECTED ADOLESCENTS DUE TO VERTICAL TRANSMISSION.
Madrid, Spain 
12 slide(s) – English – 2011-06-07
HIV characteristics and educational achievement of a cohort of HIV infected adolescents due to vertical transmission.
Gonzalez Tome,MI 1; Medin G1; Garcia Mellado I 2, Blazquez Gamero ,D1; Mellado Peña P 2,MJ; Navarro Gómez, M 3; Ramos Amador JT4; de Jose ,MI5 ; Gurbindo D3; Rojo P1, Saavedra J3, Jimenez de Ory, S 3 ;Gonzalez Granado I 1,Bellon JM 3,Prieto L 4, Guillen S 4, Ruiz Contreras J1; Muñoz MA 3 ; Beciero J6, Penin M 6, Roa MA 7, Calvo C 8 ,et al. 1Hospital 12 de Octubre, 2Hospital Carlos III, 3Hospital Gregorio Marañon, 4Hospital de Getafe, 5Hospital La Paz,6 Hospital de Alcala de Henares,7 Hospital de Mostoles, 8 Hospital Severo Ochoa.In the name of HIV adolescents cohort of Madrid. Spain.
Objectives
To assess immunovirological situation, psychosocial profile and educational achievement in a cohort of HIV vertically infected adolescents followed in 5 hospitals in Madrid.
Methods: Cross-sectional descriptive study. Data related to HIV infection were obtained every 3 months in routine visits. Patients and their parent/tutors were interviewed using a semi-structured questionnaire designed to evaluate adherence and psychosocial profile. The Strengths and Difficulties Questionnaire (SDQ) was also administered.
Results
95 adolescents (median age 16.5 years (12.4, 20.6), 97% Spanish, 10% hepatitis C). Fifty four % of their mothers acquired HIV infection by using injection drugs. Thirty four % were on C3( 18% had encephalopathy). CD4 nadir ≤ 15% (63%). Median age at HIV diagnosis (0.59 years (0, 12.2)), at the beginning of antiretroviral (3 years (0, 14.5)) and of HAART (5.7years (0.6, 18)); 42% had received ≥ 3 HAART based regimens.Nowadays, 97% of patients have CD4 ≥15% and 72% viral load ≤ 50copies/ml. Adherence ≥95% doses (48 %). Regarding educational achievement, 90% were at school or college, 19% had lost ≥ 2 years. Most common psychosocial problem concerning SDQ was hyperactivity (33%).There weren´t relationship between academic achievement and CDC stage, CD4 nadir, encephalopathy, adherence and HAART regimens; however it was related to the educational profile of their parents.
Conclusion
Although current immunovirological situation of our adolescents is good, they had a long history of failures and change of antiretroviral. An important percentage have academical difficulties but it hasn´t been related to HIV parameters; however, parent´s academic profile seems to be very important.
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