Background and aims: Autism (a condition leading to social and communication difficulties) affects males much more often than females. The explanation for this must either lie in diagnostic practice, hormones, or genetics, or a mix of all three. In this paper I summarize...(more)
The annual presentations of good Paediatric Research in a different European city have been one of the highlights of my academic life. Maybe not quite so academically pure or cutting edge as the equivalent US meetings, but more friendly and culturally as well as...(more)
Background and aims: Secretory phospholipase A2 (sPHA2) has been shown to be involved in alveolar inflammation and surfactant degradation in animal models. sPHA2 plays a role in adult RDS, but it has never been studied in human neonates with RDS. Study aim was to...(more)
The high prevalence of overweight children and adolescents will not likely respond to interventions directed at a single target in a single setting. Instead, like tobacco control, comprehensive programs that employ multiple strategies in a variety of settings are more...(more)
I propose that cardiovascular disease (CVD) risk factors are the historical residue of genetic adaptations for maternal/fetal survival of pregnancy. Four CVD risk factors - obesity, fat deposition, hyperlipemia and insulin resistance - are maternal adaptations to the fetal...(more)
After viewing this presentation the participant will be able to discuss:
- Fundamental principles of Developmental Pharmacology
- Basic features of the new European Regulation in terms of Drug Development in Children.
Background and Aims
When using medicines for children, we need to know about their efficacy and safety. Typically evidence on efficacy comes from randomised controlled trials, which are fairly straightforward to interpret, at least when they have been carried out in...(more)
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